The X family portrait: Structural insights into biological functions of X family polymerases
نویسندگان
چکیده
منابع مشابه
The X family portrait: structural insights into biological functions of X family polymerases.
The mammalian family X DNA polymerases (DNA polymerases beta, lambda, mu, and TdT) contribute to base excision repair and double-strand break repair by virtue of their ability to fill short gaps in DNA. Structural information now exists for all four of these enzymes, making this the first mammalian polymerase family whose structural portrait is complete. Here we consider how distinctive structu...
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ژورنال
عنوان ژورنال: DNA Repair
سال: 2007
ISSN: 1568-7864
DOI: 10.1016/j.dnarep.2007.05.009